Alabama authorities say a home burglary suspect has died after police used a stun gun on the man.  Birmingham police say he resisted officers who found him in a house wrapped in what looked like material from the air conditioner duct work.  The Lewisburg Road homeowner called police Tuesday about glass breaking and someone yelling and growling in his basement.  Police reportedly entered the dwelling and used a stun gun several times on a white suspect before handcuffing him.  Investigators say the man was "extremely irritated" throughout and didn't obey verbal commands.

Montgomery Education Foundation's Brain Forest Summer Learning Academy was spotlighted Wednesday at Carver High School.  The academic-enrichment program is for rising 4th, 5th, and 6th graders in the Montgomery Public School system.  Community Program Director Dillion Nettles, says the program aims to prevent learning loss during summer months.  To find out how your child can participate in next summer's program visit Montgomery-ed.org

A police officer is free on bond after being arrested following a rash of road-sign thefts in southeast Alabama.  Brantley Police Chief Titus Averett says officer Jeremy Ray Walker of Glenwood is on paid leave following his arrest in Pike County.  The 30-year-old Walker is charged with receiving stolen property.  Lt. Troy Johnson of the Pike County Sheriff's Office says an investigation began after someone reported that Walker was selling road signs from Crenshaw County.  Investigators contacted the county engineer and learned signs had been reported stolen from several roads.

NPR Politics presents the Lunchbox List: our favorite campaign news and stories curated from NPR and around the Web in digestible bites (100 words or less!). Look for it every weekday afternoon from now until the conventions.

Convention Countdown

The Republican National Convention is in 4 days in Cleveland.

The Democratic National Convention is in 11 days in Philadelphia.

NASA has released the first picture of Jupiter taken since the Juno spacecraft went into orbit around the planet on July 4.

The picture was taken on July 10. Juno was 2.7 million miles from Jupiter at the time. The color image shows some of the atmospheric features of the planet, including the giant red spot. You can also see three of Jupiter's moons in the picture: Io, Europa and Ganymede.

The Senate is set to approve a bill intended to change the way police and health care workers treat people struggling with opioid addictions.

My husband and I once took great pleasure in preparing meals from scratch. We made pizza dough and sauce. We baked bread. We churned ice cream.

Then we became parents.

Now there are some weeks when pre-chopped vegetables and a rotisserie chicken are the only things between us and five nights of Chipotle.

Parents are busy. For some of us, figuring out how to get dinner on the table is a daily struggle. So I reached out to food experts, parents and nutritionists for help. Here is some of their (and my) best advice for making weeknight meals happen.

"O Canada," the national anthem of our neighbors up north, comes in two official versions — English and French. They share a melody, but differ in meaning.

Let the record show: neither version of those lyrics contains the phrase "all lives matter."

But at the 2016 All-Star Game, the song got an unexpected edit.

At Petco Park in San Diego, one member of the Canadian singing group The Tenors — by himself, according to the other members of the group — revised the anthem.

School's out, and a lot of parents are getting through the long summer days with extra helpings of digital devices.

How should we feel about that?

Police in Baton Rouge say they have arrested three people who stole guns with the goal of killing police officers. They are still looking for a fourth suspect in the alleged plot, NPR's Greg Allen reports.

"Police say the thefts were at a Baton Rouge pawn shop early Saturday morning," Greg says. "One person was arrested at the scene. Since then, two others have been arrested and six of the eight stolen handguns have been recovered. Police are still looking for one other man."

A 13-year-old boy is among those arrested, Greg says.

Pages

FDA Says Massachusetts Pharmacy Knew Of Sterility Problems For Months

Oct 26, 2012
Originally published on October 26, 2012 5:40 pm

In a highly unusual step, the Food and Drug Administration has released a report of inspections it conduct this month of the Massachusetts pharmacy at the center of a national outbreak of fungal infections.

FDA officials say the New England Compounding Center's own environmental monitoring showed multiple instances of bacterial and fungal contamination of two "clean rooms" going back nearly nine months before an outbreak of meningitis linked to one the company's drugs.

The Centers for Disease Control and Prevention says 338 people in 18 states have suffered fungal infections linked to the company's drugs. Most were cases of meningitis and stroke, but five have been infections of knees, elbows or other joints. Twenty-five people have died.

"The investigators ... observed that no documented corrective actions were taken when the firm's own environmental monitoring showed microbial contamination above its action limit," Steven Lynn of the FDA told reporters on a conference call Friday afternoon.

An "action limit" is a threshold measurement of contamination "above what would typically be seen in a controlled sterile environment," Lynn says. He is the FDA's director of manufacturing and product quality.

In some instances, the petri dishes used to grow microbes present in environmental samples – taken from window sills, equipment, furniture, floors and other surfaces – were overflowing with bacteria or fungi in sheets "very visible to the naked eye," Lynn says.

Yet, FDA inspectors say the company didn't even bother to investigate what the microbes were.

Attempts to contact the company's attorney were not successful.

The company's foreknowledge of contamination problems and its failure to act are probably the most damning findings to come out of federal and state investigations of the Massachusetts company, a so-called "compounding pharmacy."

FDA officials repeatedly refused to answer reporters' many questions about the implications of their findings, saying they don't want to compromise an ongoing investigation.

Boston U.S. Attorney Carmen Ortiz has already opened a criminal investigation of the New England Compounding Center.

And Massachusetts Gov. Deval Patrick has said the company "misled" state officials by manufacturing drugs in bulk and shipping them nationally without a valid prescription for each patient receiving the drug, as it is required to do under its license as a compounding pharmacy.

Drug manufacturers are supposed to be licensed by the FDA and are subject to far more stringent standards called Good Manufacturing Practice and regular inspections.

Earlier this week, Massachusetts officials disclosed some results of their own investigation of the New England Compounding Center, conducted jointly with the FDA.

But the newly released federal inspection report, known as a Form 483, contains considerably more detail about conditions at the Framingham, Mass., plant – and the extent of contamination in vials of the steroid methylprednisolone acetate, the drug involved in most of the fungal infections.

For instance:

  • Eighty-three of 321 vials of the drug still at New England Compounding contained "a greenish-black foreign matter" visible to the naked eye.

  • Seventeen of the 321 vials contained "white filamentous material."

  • When an FDA lab analyzed 50 vials of methylprednisolone, all of them had what the agency calls "viable microbial growth."

The inspectors also noted that the air conditioning units serving the "clean rooms" where drugs are formulated were customarily turned off overnight. Lynn says this "is not typical practice for a clean room," since temperatures need to be kept constant to retard microbial growth.

The FDA also noted that the pharmacy "is abutted to the rear and along the left parking area by a recycling facility that handles such materials as mattresses and plastics." Rooftop air-handling units for the pharmacy were located about 100 feet from the dusty recycling facility.

Inspectors said an autoclave – used to sterilize equipment used in manufacturing – had puddles of water in the base of its chamber, a possible source of microbial growth.

The report cites many instances of "greenish yellow," "yellowish," "greenish" and "dark" residues on equipment and surfaces.

A boiler 30 feet from the entrance to a "prep room" was leaking water, and "wet floor surfaces around the boiler appeared to be soiled with thick white debris and thick, black, granular material," the report said.

FDA officials refused to characterize the seriousness of what they found, although Paul Teitell, the agency's acting director of operations for its Office of Medical Products and Tobacco, said: "Manufacturers and compounding firms have the responsibility to manufacture quality drugs and ensure there is no breakdown in supplies or processes that would cause contamination."

Copyright 2014 NPR. To see more, visit http://www.npr.org/.