New British Prime Minister Theresa May announced six members of her Cabinet Wednesday.

Amid a sweeping crackdown on dissent in Egypt, security forces have forcibly disappeared hundreds of people since the beginning of 2015, according to a new report from Amnesty International.

It's an "unprecedented spike," the group says, with an average of three or four people disappeared every day.

The Republican Party, as it prepares for its convention next week has checked off item No. 1 on its housekeeping list — drafting a party platform. The document reflects the conservative views of its authors, many of whom are party activists. So don't look for any concessions to changing views among the broader public on key social issues.

Many public figures who took to Twitter and Facebook following the murder of five police officers in Dallas have faced public blowback and, in some cases, found their employers less than forgiving about inflammatory and sometimes hateful online comments.

As Venezuela unravels — with shortages of food and medicine, as well as runaway inflation — President Nicolas Maduro is increasingly unpopular. But he's still holding onto power.

"The truth in Venezuela is there is real hunger. We are hungry," says a man who has invited me into his house in the northwestern city of Maracaibo, but doesn't want his name used for fear of reprisals by the government.

The wiry man paces angrily as he speaks. It wasn't always this way, he says, showing how loose his pants are now.

Ask a typical teenage girl about the latest slang and girl crushes and you might get answers like "spilling the tea" and Taylor Swift. But at the Girl Up Leadership Summit in Washington, D.C., the answers were "intersectional feminism" — the idea that there's no one-size-fits-all definition of feminism — and U.N. climate chief Christiana Figueres.

Copyright 2016 NPR. To see more, visit http://www.npr.org/.

Copyright 2016 NPR. To see more, visit http://www.npr.org/.

Copyright 2016 NPR. To see more, visit http://www.npr.org/.

Copyright 2016 NPR. To see more, visit http://www.npr.org/.

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Amgen To Buy Onyx In $10.4 Billion Deal

Aug 27, 2013
Originally published on August 27, 2013 5:13 am

Transcript

RENEE MONTAGNE, HOST:

NPR's business news starts with a major biotech deal.

Amgen, the world's largest biotech company, is buying Onyx Pharmaceuticals for nearly $10.5 billion.

As NPR's Wendy Kaufman reports, Amgen has high hopes for Onyx's cancer drugs.

WENDY KAUFMAN, BYLINE: Amgen has cancer-related medicines, but for the most part they relieve side effects of chemotherapy, they don't act on the cancer itself.

And analyst Mark Schoenebaum of the stock research firm ISI Group says Amgen wanted a piece of that action.

MARK SCHOENEBAUM: They can't rely forever on their current drugs which ease the side effects of chemotherapy because the long-term trends indicate that chemotherapy use is on the decline as new, more effective, more targeted, less toxic drugs take over for cancer therapy.

KAUFMAN: With this acquisition, the company gets among other drugs - one called Kyprolis, it's used to treat multiple myeloma - bone marrow cancer. Cancer drugs in general have become a huge part of the pharmaceutical industry and are expected to become the number one category for sales within five years.

Analyst Gene Mack of Brean Capital says the market for multiple myeloma drugs could be particularly strong. He believes Kyprolis could eventually be a major player in that market with annual sales of about $2 billion.

GENE MACK: That would be meaningful to anybody's income statement for sure.

KAUFMAN: Wall Street generally applauded Amgen's acquisition, but the deal comes with significant risks. For example, while Kyprolis has shown promise, it's not yet known how effective it will be over the long term, and the drug faces entrenched competition from other drug makers.

Wendy Kaufman, NPR News. Transcript provided by NPR, Copyright NPR.